Dr. Greg Korbutt & Dr. Andrew Pepper
Revolutionizing Islet Cell Transplantation
The Edmonton Protocol — a world-famous procedure for transplanting insulin-producing cells, born in Alberta. However, it currently faces two major hurdles: a shortage of donor cells and the need for lifelong anti-rejection drugs.
Drs. Greg Korbutt and Andrew Pepper are leading the charge to overcome these challenges with a three-pillar approach to research.
Breaking Barriers to a Universal Cure
“By addressing key challenges in transplantation, this research is paving the way for transformative diabetes care that could benefit countless individuals worldwide.”
Improving T1D Outcomes
This research focuses on improving the survival, function, and durability of transplanted islet cells. Rather than replacing existing therapies, it strengthens them — ensuring that each donated organ and each transplant delivers the greatest possible benefit to patients.
Sourcing & Survival
The Edmonton Protocol, a revolutionary treatment for type 1 diabetes, faces two key challenges: the shortage of donor islet cells and the reliance on anti-rejection medications.
Exploring Other Sources
Drs. Greg Korbutt and Andrew Pepper are leading the charge to address these barriers with innovative research
Developing Targeted Anti-Rejection Medication: Aiming to create a less invasive, safer alternative to traditional immune suppression.
Exploring Neonatal Porcine Islet Cells: Investigating the use of pig islet cells as a safe and limitless supply of insulin-producing cells for transplantation.
By addressing key challenges in transplantation, this research is paving the way for transformative diabetes care that could benefit countless individuals worldwide.
Why this is a breakthrough:
Improved islet preparation to increase cell survival before transplant
Explored ways to protect islets after transplant for better long-term success
Supported specialized equipment critical to transplant research
Steady progress delivering real improvements in clinical practice
The ECECAF Impact
Vital Tools for Clinical Application
Advancements of this scale require specialized technology. With the generous support of the Edmonton Civic Employees Charitable Assistance Fund (ECECAF), Drs. Korbutt and Pepper acquired a crucial piece of equipment for advancing their research.
This machine will enhance the team’s ability to refine their methods and bring their innovative solutions closer to clinical application.
Align your brand with world-class innovation! Corporate donations and sponsorships provide the high-level funding needed for large-scale clinical trials.
ECECAF representatives present a cheque to ADF at the Hummingbirds Awards Gala 2024
Be Part of the Change
The journey to a world without diabetes is a shared mission.
Major breakthroughs happen because of your support. Individuals, community groups, and businesses are invited to join the Alberta Diabetes Foundation in funding discoveries like this. Every dollar stays right here in Alberta!
